Research group Gloveli - Cellular and Network Physiology Group

Research Fields

  • Axonal activity during network oscillations
  • Role of interneurons in hippocampal gamma and theta frequency network oscillations
  • Perisomatic control of hippocampal pyramidal cell neuronal excitability and plasticity
  • Functional and structural alterations in hippocampal inhibitory innervations in temporal lobe epilepsy

Methods

  • In vitro field, intracellular and Patch clamp techniques
  • Somatic and axonal patch-clamp recordings
  • In vivo LFP recordings
  • Neuromorphology and Immunohistochemistry
  • Mouse model of temporal lobe epilepsy

Funding

Opens external link in current windowDFG GL 254/5-2: Dynamic of axonal activity during fast network oscillations and plasticity

 Einstein Foundation Berlin Opens external link in current windowA-2013-176: The axonal code of information processing

Opens external link in current windowNeuroCure Postdoctoral Researcher Fellowship (T. Dugladze): Neuronal network dynamics in the normal and epileptic brain

Publications

Dugladze T, Maziashvili N, Börgers C, Gurgenidze S, Häussler U, Winkelmann A, Haas CA, Meier JC, Vida I, Kopell NJ, Gloveli T (2013) GABA(B) autoreceptor-mediated cell type-specific reduction of inhibition in epileptic mice. Proc Natl Acad Sci U S A 110:15073-15078.

Opens external link in current windowPubmed

Dugladze T, Schmitz D, Whittington MA, Vida I, Gloveli T (2012) Segregation of axonal and somatic activity during fast network oscillations. Science 336:1458-1461.

Opens external link in current windowPubmed

Dugladze T, Vida I, Tort AB, Gross A, Otahal J, Heinemann U, Kopell NJ, Gloveli T (2007) Impaired hippocampal rhythmogenesis in a mouse model of mesial temporal lobe epilepsy. Proc Natl Acad Sci USA 104:17530-17535.

Opens external link in current windowPubmed

 

Please find further information on Opens external link in current windowglovelilab.wordpress.com and  Opens external link in current windowglovelilab.charite.de/en

Team

Dr. Tamar Dugladze:
 - Tel: 528 214
 - tamar.dugladze[at]charite.de

Dr. Peter Bäuerle:
 - Tel: 528 217
 - peter.baeuerle[at]charite.de

Dr. Julio Santos Torres:
 - Tel: 539 021
 - julio.santos-torres[at]charite.de

Linda Brenndörfer:
 - Tel: 528 217
 - linda.brenndoerfer[at]charite.de

Melanie Timmler: - Tel: 539 021 - melanie.timmler[at]charite.de

Prof. Dr. rer. nat. Tengis Gloveli

Projektgruppenleitung Zell - u. Netzwerkphysiologie

CharitéUniversitätsmedizin Berlin

CCM: Campus Charité Mitte

Charité Center Basic Sciences CC 2

Institute of Neurophysiology

Projektgruppe Gloveli

Postal address:

Institut für Neurophysiologie CCM, CharitéCrossOver Virchowweg 6

10117 Berlin

Internal address:

Charitéplatz 1

t: +49 30 450 528 214 +49 30 450 528 217

f: +49 30 450 539 950

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