Research group Geiger - Physiology and Pathophysipology of Cortical Interneurons, Axons, and Presynaptic Boutons

Research focus

  • Molecular physiology, plasticity and synaptic function and dysfunction of interneuron subtypes in cortical networks
  • Network alterations and behavioural symptoms generated by interneuron dysfunction in animal models
  • Coding principles and energy efficiency of electrical signaling in cortical axons

Methods

  • Somatic and presynaptic patch-clamp recordings in acute slices of rodent brain
  • Paired recordings from synaptically coupled neurons
  • Quantitative single-cell RT-qPCR after electrophysiological characterization
  • Adeno-associated virus mediated alterations of neuronal expression patterns in the rodent brain
  • Laser-capture microdissection and transcriptome analyses of immunohistochemically identified neurons
  • Animal models of psychiatric disorders: Correlation analysis between behavioural phenotype, molecular deviations and electrophysiological alterations of neurons and synaptic transmission (future project)

Funding

Opens external link in current windowNeurocure

Group member

For contact purposes please email to Sekretariat-Neurophysiologie(at)charite.de

Dr. Henrik Alle

Dr. Stephanie Braud

Sonja Frosinski (Secretary)

Dr. Christine Gebhardt

Constantin Klisch

Dr. Benjamin Marquez-Klaka

Dr. Henrike Planert

Yangfan Peng

Dr. Davide Raccuglia

Dr. Stefanie Schinkel

Roland Schneider (Technician)

Dr. Katrin Schulze

Andrea Wilke (Technician)

 

MD/PhD students:

Michael Hadler

Julia Neugebauer

Veronica Rignall

Leon-Amadeus Steiner

John Thiede

Vera Wuntke

Zhen Hao Xue

Daniela Zurkan

 

Alumnis:

Kerstin Rückwardt

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Publications of the research group Geiger

Group leader

Portaitbild von Prof. Dr. rer nat Jörg Geiger
Prof. Dr. rer.nat Jörg Geiger
t: +49 30 450 528 152

Secretary

Mrs. Sonja Frosinski
t: +49 30 450 528 152
f: +49 30 450 539 950

Postal address:

Charité CCM
Institut für Neurophysiologie
Charitéplatz 1
10117 Berlin

Office (Campus address):

CCO
Virchowweg 6 Floor 02 Room 340